The Global Nanobodies Market Growth Accelerated By Emerging Applications
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Nanobodies Market |
Nanobodies refer to single
variable domains of antibodies called nanobodies that are derived from
heavy-chain antibodies that naturally occur in camelid animals. Nanobodies are
advantageous over conventional antibodies as they are remarkably small in size,
robust, and versatile. They can recognize poorly antigenic sites on targets and
induce conformation changes. Nanobodies are increasingly being used for therapeutic
and diagnostic applications in several disease areas including oncology,
inflammatory conditions, and infectious diseases. Some key therapeutic
applications of nanobodies include blocking receptors and ligands, inhibiting
enzymes, neutralizing toxins and viruses, modulating signaling pathways,
targeting tumors, and facilitating drug delivery.
The global nanobodies market is
estimated to be valued at US$ 1256.49 Bn
in 2023 and is expected to exhibit a CAGR
of 4.5% over the forecast period 2023 to 2030, as highlighted in a new
report published by Coherent Market Insights.
Market Dynamics:
Increasing therapeutic
applications of nanobodies is the major driver estimated to propel the growth
of global nanobodies market over the forecast period. With advancing nanobody
technology, newer therapeutic applications are being explored in several
disease areas including oncology and infectious diseases. Growing R&D
investments by pharmaceutical companies and biotech firms into nanobodies for
developing targeted and safe biological therapeutics represents another key
driver. Nanobodies provide promising opportunities for developing next
generation therapeutics with high affinity and selectivity to target proteins
or pathogens which has boosted investments in nanobody technology. However,
challenges associated with clinical translation and high development costs are
some factors expected to hamper the market growth.
SWOT Analysis
Strength: Nanobodies have
advantages over traditional antibodies such as their small size which allows
better tissue penetration. Their robust stability and solubility allows ease of
production. Nanobodies can be genetically engineered for improved affinity and
specificity.
Weakness: Early stage research
and development may limit immediate commercialization. High production costs
compared to traditional antibodies is also a weakness.
Opportunity: Growing biologics
and biopharmaceutical industries offer opportunities for nanobody applications
in research, diagnostics, and therapy. Rising demand for precision medicine and
personalized healthcare further opens opportunities.
Threats: Traditional monoclonal
antibodies are well established with extensive clinical use, posing competitive
threats. Stringent regulations for approval may slow market adoption of new
applications.
Key Takeaways
The Global
Nanobodies Market Size is expected to witness high growth. Advancements
in recombinant technologies for large scale production have boosted the market.
The market captured revenue of US$ 1256.49 Bn in 2023 and is projected to reach
over US$ 1800 Bn by 2030 at a CAGR of 4.5% during the forecast
period.
Regional analysis reveals North America currently dominates due to
extensive R&D and a large biopharmaceutical industry in the region.
However, Asia Pacific is poised to offer the highest growth led by China,
India, and South Korea. Establishing local production facilities, growing
biologics market, and improving research infrastructure will drive the region.
Key players operating in the nanobodies market are 3M, Creative
Biolabs, Ablynx, ChromoTek, Thermo Fisher Scientific. 3M and Creative Biolabs
offer a wide portfolio of nanobodies for research and diagnostic applications.
Ablynx has clinically validated nanobody therapeutics. Thermo Fisher Scientific
provides reagents, expression systems and services for nanobody development.
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